Bovine aortic endothelial cells display macrophage-like properties towards acetylated 125I-labelled low density lipoprotein

O Stein, Y Stein - Biochimica et Biophysica Acta (BBA)-Lipids and Lipid …, 1980 - Elsevier
Bovine aortic endothelial cells in culture were shown to take up and degrade acetylated 125
I-labelled low density lipoproteins (125 I-acetylated LDL) in preference to 125 I-labelled low
density lipoproteins (LDL). The confluent cultures of endothelial cells had a higher rate of
degradation of 125 I-acetylated LDL than did subconfluent cells. The ratio of degradation of
125 I-acetylated LDL to 125 I-LDL was 3–9 in the case of the endothelial cells, 0.06–0.11 for
aortic smooth muscle cells and 18 for mouse peritoneal macrophages. The uptake and …