Retinal blood flow alterations during progression of diabetic retinopathy

A Yoshida, GT Feke, J Morales-Stoppello… - Archives of …, 1983 - jamanetwork.com
• Alterations in retinal blood flow during the progression of diabetic retinopathy were studied
using the dye-dilution technique. Mean fluorescein circulation times were measured in
retinal arteriovenous segments with a two-point fluorophotometer in 48 diabetic patients and
20 normal controls. Monochromatic fundus photographs were used to determine vessel
diameters. Segmental blood flow (SBF) increased with the progression of background
diabetic retinopathy. In patients with distinct capillary closure, SBF was significantly higher …