The role of platelet membrane glycoproteins Ib and IIb‐IIIa in platelet adherence to human artery subendothelium
KS Sakariassen, PFEM Nievelstein… - British journal of …, 1986 - Wiley Online Library
KS Sakariassen, PFEM Nievelstein, BS Coller, JJ Sixma
British journal of haematology, 1986•Wiley Online LibraryPlatelet adherence to human artery subendothelium in blood from eight normal subjects,
four patients with Glanzmann's thrombasthenia (deficiency of platelet membrane
glycoproteins IIb and IIIa: GPIIb‐IIIa), two patients with Bernard‐Soulier syndrome
(deficiency of platelet membrane glycoprotein Ib: GPIb) and one patient with von
Willebrand's disease (VWD subtype III, deficient in factor VHI‐von Willebrand factor: FVIII‐
VWF) was compared at various wall shear rates (300, 500, 1000, 1800 and 2500 s‐1).
four patients with Glanzmann's thrombasthenia (deficiency of platelet membrane
glycoproteins IIb and IIIa: GPIIb‐IIIa), two patients with Bernard‐Soulier syndrome
(deficiency of platelet membrane glycoprotein Ib: GPIb) and one patient with von
Willebrand's disease (VWD subtype III, deficient in factor VHI‐von Willebrand factor: FVIII‐
VWF) was compared at various wall shear rates (300, 500, 1000, 1800 and 2500 s‐1).
Summary
Platelet adherence to human artery subendothelium in blood from eight normal subjects, four patients with Glanzmann's thrombasthenia (deficiency of platelet membrane glycoproteins IIb and IIIa: GPIIb‐IIIa), two patients with Bernard‐Soulier syndrome (deficiency of platelet membrane glycoprotein Ib: GPIb) and one patient with von Willebrand's disease (VWD subtype III, deficient in factor VHI‐von Willebrand factor: FVIII‐VWF) was compared at various wall shear rates (300, 500, 1000, 1800 and 2500 s‐1).
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