The putative 116 kDa osteoclast specific vacuolar proton pump subunit has ubiquitous tissue distribution
BB Scott, CG Chapman - European journal of pharmacology, 1998 - Elsevier
BB Scott, CG Chapman
European journal of pharmacology, 1998•ElsevierThe pharmacological profile of the osteoclast proton pump has been demonstrated to be
unique and to be the most active of all acid transport systems thus far studied. The recently
reported putative 116 kDa osteoclast specific vacuolar proton pump subunit could possibly
explain the unique nature of this proton pump. Here, we demonstrate however, that the
osteoclast 116 kDa subunit is not osteoclast specific but has ubiquitous expression in
human tissue.
unique and to be the most active of all acid transport systems thus far studied. The recently
reported putative 116 kDa osteoclast specific vacuolar proton pump subunit could possibly
explain the unique nature of this proton pump. Here, we demonstrate however, that the
osteoclast 116 kDa subunit is not osteoclast specific but has ubiquitous expression in
human tissue.
The pharmacological profile of the osteoclast proton pump has been demonstrated to be unique and to be the most active of all acid transport systems thus far studied. The recently reported putative 116 kDa osteoclast specific vacuolar proton pump subunit could possibly explain the unique nature of this proton pump. Here, we demonstrate however, that the osteoclast 116 kDa subunit is not osteoclast specific but has ubiquitous expression in human tissue.
Elsevier