Molecular aspects of osteoclast function

TJ Hall, TJ Chambers - Inflammation Research, 1996 - Springer
TJ Hall, TJ Chambers
Inflammation Research, 1996Springer
In this article we have overviewed recent important advances in understanding the
molecular mechanisms involved in osteoclastic bone resorption. Specifically, new findings
relating to osteoclast activation and the process of bone resorption are reviewed and a
current overall model of how osteoclasts resorb bone is presented. Controversial research
topics concerning the regulation of osteoclast activity are also critically discussed.
Abstract
In this article we have overviewed recent important advances in understanding the molecular mechanisms involved in osteoclastic bone resorption. Specifically, new findings relating to osteoclast activation and the process of bone resorption are reviewed and a current overall model of how osteoclasts resorb bone is presented. Controversial research topics concerning the regulation of osteoclast activity are also critically discussed.
Springer