Assignment [sup 1] of the melanocortin 4 receptor (MC4R) gene to human chromosome band 18q22 by in situ hybridisation and radiation hybrid mapping.

D Sundaramurthy, DA Campbell… - Cytogenetics & Cell …, 1998 - search.ebscohost.com
D Sundaramurthy, DA Campbell, JP Leek, AF Markham, LF Pieri
Cytogenetics & Cell Genetics, 1998search.ebscohost.com
Melanocortins are peptide hormones derived from pro-opiomelanocortin (POMC). They
have an important role in regulating melanocyte pigmentation. They also play a part in a
wide variety of physiological processes including enhancement of learning and memory and
thermoregulation. They mediate their effects through G-protein coupled receptors by
stimulating adenylate cyclase. These receptors show a diversity of subtypes though they all
belong to the same super-family.
Abstract
Melanocortins are peptide hormones derived from pro-opiomelanocortin (POMC). They have an important role in regulating melanocyte pigmentation. They also play a part in a wide variety of physiological processes including enhancement of learning and memory and thermoregulation. They mediate their effects through G-protein coupled receptors by stimulating adenylate cyclase. These receptors show a diversity of subtypes though they all belong to the same super-family.
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