Immune privilege, T-cell tolerance, and tissue-restricted autoimmunity

JW Streilein, M Takeuchi, AW Taylor - Human immunology, 1997 - Elsevier
The eye is one of several specialized organs/tissues that display immune privilege, ie sites
that permit foreign tissue grafts to enjoy prolonged (or even indefinite) survival. Immune
privilege is an active, rather than a passive, process in which specialized tissues/sites and
the immune system collaborate in providing immune protection without the risk of
immunopathogenic injury to the tissue itself. Among the mechanisms that have been found
to contribute to immune privilege is tolerance of peripheral T cells. Over the past few years …