Phosphorylcholine: friend or foe of the immune system?
W Harnett, MM Harnett - Immunology today, 1999 - cell.com
W Harnett, MM Harnett
Immunology today, 1999•cell.comPhosphorylcholine (PC) is a structural component of a variety of prokaryotic and eukaryotic
pathogens. In some cases, PC in infectious agents can benefit the infected host due to its
targeting by both the innate and adaptive immune responses. However, as discussed here,
PC exhibits a surprising range of immunomodulatory properties that might be to the
detriment of the host.
pathogens. In some cases, PC in infectious agents can benefit the infected host due to its
targeting by both the innate and adaptive immune responses. However, as discussed here,
PC exhibits a surprising range of immunomodulatory properties that might be to the
detriment of the host.
Abstract
Phosphorylcholine (PC) is a structural component of a variety of prokaryotic and eukaryotic pathogens. In some cases, PC in infectious agents can benefit the infected host due to its targeting by both the innate and adaptive immune responses. However, as discussed here, PC exhibits a surprising range of immunomodulatory properties that might be to the detriment of the host.
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