[PDF][PDF] Studies on morpholinosphingolipids: potent inhibitors of glucosylceramide synthase

KG Carson, B Ganem, NS Radin, A Abe, JA Shayman - 1994 - deepblue.lib.umich.edu
KG Carson, B Ganem, NS Radin, A Abe, JA Shayman
1994deepblue.lib.umich.edu
STUDIES ON MORPHOLINOSPHINGOLIPIDS: POTENT INHIBITORS OF
GLUCOSYLCERAMIDE SYNTHASE Page 1 Tcmzhedroa Letters. Vol. 35. No. 17. pp. 265.9~26621994
Elseviu Science L&l Rimed in Great Britain oo4o-4039194 s6.ooto.orl 0040-4039(94)EO393-C
STUDIES ON MORPHOLINOSPHINGOLIPIDS: POTENT INHIBITORS OF
GLUCOSYLCERAMIDE SYNTHASE Kenneth G. Carson and Bruce Ganem* Department of
Chemistry. Baker Laboratory Cornell University, Ithaca, NY 14853-1301 USA Noman S. Radin …
Synthetic 1-morpholino-1-deoxyceramides were designed to inhibit glucosylceramide synthase. The most potent inhibitor 2a possesses the unnatural R,R-configuration of D-threo-sphingosine.
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