Reduced serotonin uptake by spontaneously hypertensive rat platelets
R Prina, E Dolfini, T Mennini, A Palermo, A Libretti - Life Sciences, 1981 - Elsevier
R Prina, E Dolfini, T Mennini, A Palermo, A Libretti
Life Sciences, 1981•ElsevierAbstract Platelets of Spontaneous Hypertensive (SH) rats show a significant reduction in
serotonin uptake, compared with that of rats with normal blood pressure. The difference was
due to the V max, which was about 40% of normals, while the K m values were almost
constant. The possible analogy between blood platelets and serotonergic nerve terminals in
SH rats is considered in the evaluation of the results.
serotonin uptake, compared with that of rats with normal blood pressure. The difference was
due to the V max, which was about 40% of normals, while the K m values were almost
constant. The possible analogy between blood platelets and serotonergic nerve terminals in
SH rats is considered in the evaluation of the results.
Abstract
Platelets of Spontaneous Hypertensive (SH) rats show a significant reduction in serotonin uptake, compared with that of rats with normal blood pressure. The difference was due to the Vmax, which was about 40% of normals, while the Km values were almost constant. The possible analogy between blood platelets and serotonergic nerve terminals in SH rats is considered in the evaluation of the results.
Elsevier