Identification of a membrane glycoprotein associated with haemopoietic progenitor cells

FE Katz, R Tindle, DR Sutherland, MF Greaves - Leukemia research, 1985 - Elsevier
Abstract A monoclonal antibody (3C5) is described which selectively binds to progenitor cell
populations in human bone marrow and foetal liver. Mature, lymphoid (T, B) colony forming
cells do not express the antigen. The antibody identifies a cell surface glycoprotein of mol.
wt∼ 100,000 which might have an important regulatory role in early haemopoietic
differentiation.