Modification of proteins and lipids by myeloperoxidase

SL Hazen, FF Hsu, JP Gaut, JR Crowley… - Methods in …, 1999 - Elsevier
Publisher Summary This chapter describes methods for identifying and quantifying oxidative
damage to proteins, lipids, and low density lipoprotein (LDL) that has resulted from
myeloperoxidase activity. It discusses general procedures for working with hypochlorous
acid 1 (HOC1) and other reactive halogenating agents. The identification of protein and lipid
oxidation products that are specifically generated by the myeloperoxidase system, together
with the development of methods to detect low levels of these markers in tissues, enables …