[HTML][HTML] T cell responses and viral escape

A McMichael - Cell, 1998 - cell.com
A McMichael
Cell, 1998cell.com
Virus infections are normally controlled, and often eliminated, by T lymphocyte responses.
Antibody may also contribute but is probably more important in prophylaxis against repeat
exposure with the same pathogen. Some viruses are not eliminated and it is becoming clear
that many of these have evolved immune evasion mechanisms; herpes viruses, for instance,
encode proteins that interfere with the presentation of viral peptide antigens to T cells
(reviewed in
Virus infections are normally controlled, and often eliminated, by T lymphocyte responses. Antibody may also contribute but is probably more important in prophylaxis against repeat exposure with the same pathogen. Some viruses are not eliminated and it is becoming clear that many of these have evolved immune evasion mechanisms; herpes viruses, for instance, encode proteins that interfere with the presentation of viral peptide antigens to T cells (reviewed in
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