Late consequences of acute ischemic injury to a solitary kidney
ME Pagtalunan, JL Olson, NL Tilney… - Journal of the American …, 1999 - journals.lww.com
The sequelae of acute ischemic injury to a solitary kidney were assessed in rats subjected to
right nephrectomy and transient occlusion of the left renal artery; control rats underwent right
nephrectomy alone. Incomplete recovery from ischemic injury at 2 wk (serum creatinine
levels of 1.1±0.2 versus 0.5±0.1 mg/dl, P< 0.05 for ischemia versus control) was followed by
deterioration of renal function at 20 wk (serum creatinine levels of 1.7±0.4 versus 0.7±0.1
mg/dl, P< 0.05 for ischemia versus control). Morphologic studies showed that impairment of …
right nephrectomy and transient occlusion of the left renal artery; control rats underwent right
nephrectomy alone. Incomplete recovery from ischemic injury at 2 wk (serum creatinine
levels of 1.1±0.2 versus 0.5±0.1 mg/dl, P< 0.05 for ischemia versus control) was followed by
deterioration of renal function at 20 wk (serum creatinine levels of 1.7±0.4 versus 0.7±0.1
mg/dl, P< 0.05 for ischemia versus control). Morphologic studies showed that impairment of …