Alpha 2-macroglobulin-proteinase complexes, plasminogen activator inhibitor type-1-plasminogen activator complexes, and receptor-associated protein bind to a …
SK Moestrup, TL Holtet, M Etzerodt… - Journal of Biological …, 1993 - ASBMB
A region containing sites for ligand binding was localized in the 4525-amino acid residue
alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein (alpha
2MR/LRP) by ligand-and immunoblotting of proteinase and CNBr digests of the purified
human placental protein. 125I-Labeled rat alpha 1-macroglobulin light chain, urokinase-
plasminogen activator inhibitor type-1 complex, and alpha 2MR-associated protein all
bound to a 75-kDa CNBr-generated fragment (68 kDa after deglycosylation). In addition to …
alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein (alpha
2MR/LRP) by ligand-and immunoblotting of proteinase and CNBr digests of the purified
human placental protein. 125I-Labeled rat alpha 1-macroglobulin light chain, urokinase-
plasminogen activator inhibitor type-1 complex, and alpha 2MR-associated protein all
bound to a 75-kDa CNBr-generated fragment (68 kDa after deglycosylation). In addition to …