Continuous intraventricular infusion of neuropeptide Y evokes episodic food intake in satiated female rats: effects of adrenalectomy and cholecystokinin
SP Kalra, MG Dube, PS Kalra - Peptides, 1988 - Elsevier
In these studies the pattern of feeding behavior during continuous intraventricular (IVT)
infusion of NPY for 4 hr in the satiated female rat was monitored. Whereas saline infusion
was ineffective, each of the three doses of NPY (117, 470 or 1175 pmol/hr) increased
feeding during the entire 4 hr infusion and 2 hr postinfusion period. The cumulative food
intake at the end of 4 hr of NPY infusion was enhanced in a dose-related fashion between 0,
117 and 470 pmol/hr; at 1175 pmol/hr food intake plateaued. In addition, the latency to …
infusion of NPY for 4 hr in the satiated female rat was monitored. Whereas saline infusion
was ineffective, each of the three doses of NPY (117, 470 or 1175 pmol/hr) increased
feeding during the entire 4 hr infusion and 2 hr postinfusion period. The cumulative food
intake at the end of 4 hr of NPY infusion was enhanced in a dose-related fashion between 0,
117 and 470 pmol/hr; at 1175 pmol/hr food intake plateaued. In addition, the latency to …