Malignant and benign tumors in patients with neurofibromatosis type 1 in a defined Swedish population

MET Zöller, B Rembeck, A Odén… - … Journal of the …, 1997 - Wiley Online Library
MET Zöller, B Rembeck, A Odén, M Samuelsson, L Angervall
Cancer: Interdisciplinary International Journal of the American …, 1997Wiley Online Library
Seventy adult patients with neurofibromatosis type 1 were followed for 12 years, and from
this group 11 malignant tumors were reported to the Swedish Cancer Registry. The
occurrence of malignant tumors in this group was four times greater than expected in the
general population. From the birth of these patients up to 1990, 13 carcinomas, 5 sarcomas,
1 malignant melanoma, and 4 pheochromocytomas were found.
Seventy adult patients with neurofibromatosis type 1 were followed for 12 years, and from this group 11 malignant tumors were reported to the Swedish Cancer Registry. The occurrence of malignant tumors in this group was four times greater than expected in the general population. From the birth of these patients up to 1990, 13 carcinomas, 5 sarcomas, 1 malignant melanoma, and 4 pheochromocytomas were found.
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