Thickness, cross-sectional areas and depth of invasion in the prognosis of cutaneous melanoma.

A Breslow - Annals of surgery, 1970 - ncbi.nlm.nih.gov
A Breslow
Annals of surgery, 1970ncbi.nlm.nih.gov
Materials and Methods The 98 patients in this study were all free of recurrent or metastatic
disease and none had satellite nodules when first seen at the George Washington
University Hos-pital. None of the lesions were related to an antecedent lentigo malignum
(melanotic freckle of Hutchinson). Their ages ranged from 18 to 80 (average 47). Forty-six
were men and 52, women. Sixteen had lesions of the head or neck; 50, of an extremity; and
32, of the trunk. Following operation 71 remained free of disease for 5 or more years, while …
Materials and Methods The 98 patients in this study were all free of recurrent or metastatic disease and none had satellite nodules when first seen at the George Washington University Hos-pital. None of the lesions were related to an antecedent lentigo malignum (melanotic freckle of Hutchinson). Their ages ranged from 18 to 80 (average 47). Forty-six were men and 52, women. Sixteen had lesions of the head or neck; 50, of an extremity; and 32, of the trunk.
Following operation 71 remained free of disease for 5 or more years, while 27 de-veloped metastaticor recurrent disease. Patients who died of unknown causes, who died in less than 5 years without melanoma and those lost to follow-up were excluded. Follow-up was 92% o.
ncbi.nlm.nih.gov