Interaction of the hemochromatosis gene product HFE with transferrin receptor modulates cellular iron metabolism
RS Eisenstein - Nutrition reviews, 1998 - academic.oup.com
Nutrition reviews, 1998•academic.oup.com
Mutations of a novel MHC class I-like protein, termed HFE, have been found in the vast
majority of patients with the iron overload disease heredity hemochromatosis. Identification
of HFE is likely to shed light on one of the major enigmas of mammalian iron homeostasis:
How is intestinal iron absorption regulated?
majority of patients with the iron overload disease heredity hemochromatosis. Identification
of HFE is likely to shed light on one of the major enigmas of mammalian iron homeostasis:
How is intestinal iron absorption regulated?
Abstract
Mutations of a novel MHC class I-like protein, termed HFE, have been found in the vast majority of patients with the iron overload disease heredity hemochromatosis. Identification of HFE is likely to shed light on one of the major enigmas of mammalian iron homeostasis: How is intestinal iron absorption regulated?
Oxford University Press