As Theodore Friedmann notes in “Overcoming the Obstacles to Gene Therapy” on page 96
of this issue, many efforts at developing gene therapy employ modified viruses to shuttle into
human cells genes coding for potentially therapeutic proteins. The aim is to induce cells that
are invaded by a virus to transfer the gene to the cell nucleus. The cells should then
“express,” or manufacture, the needed protein specified by the gene. Viruses are effective at
transferring genes into cells because they have evolved specialized mechanisms that allow …

US5399346A - Gene therapy - Google Patents US5399346A - Gene therapy - Google Patents
Gene therapy Download PDF Info Publication number US5399346A US5399346A
US08/220,175 US22017594A US5399346A US 5399346 A US5399346 A US 5399346A US
22017594 A US22017594 A US 22017594A US 5399346 A US5399346 A US 5399346A
Authority US United States Prior art keywords cells til gene human cell Prior art date 1989-06-14
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