Different time course patterns of local expression of delayed-type hypersensitivity to sheep red blood cells in mice
B Hurtrel, MA Maire, M Hurtrel, PH Lagrange - Cellular immunology, 1992 - Elsevier
The delayed-type hypersensitivity (DTH) reaction, a peripheral expression of cell-mediated
immunity is still a crucial in vivo immunological test. Nevertheless, the biological significance
of its time course remains unclear. Thus, an exhaustive study of DTH was undertaken in
mice immunized with increasing doses of sheep red blood cells (SRBC) inoculated
intravenously (iv) or subcutaneously. The results showed that overall DTH reactions peaked
at 18 hr except in mice iv immunized with the lowest doses (10 5 and 10 6) and elicited at …
immunity is still a crucial in vivo immunological test. Nevertheless, the biological significance
of its time course remains unclear. Thus, an exhaustive study of DTH was undertaken in
mice immunized with increasing doses of sheep red blood cells (SRBC) inoculated
intravenously (iv) or subcutaneously. The results showed that overall DTH reactions peaked
at 18 hr except in mice iv immunized with the lowest doses (10 5 and 10 6) and elicited at …