Hypercholesterolemia encompasses a heterogenous group of disorders in lioid metabolism
characterized by ilevated levels of plasma total cholesterol and low density lipoprotein (LDL)-
derived cholesterol. It is one of the few independent risk factors definitively linked to
increased mor-..... Ixalty and mortality due to myocardial infarction and considerable effort
has been directed towards the development of effective hypocholesterolemic agents.
Cholesterol enters the bodv pool from only two sources, either