Resistance to multiple hormones in patients with pseudohypoparathyroidism: association with deficient activity of guanine nucleotide regulatory protein
MA Levine, RW Downs Jr, AM Moses… - The American Journal of …, 1983 - Elsevier
Pseudohypoparathyroidism type I is characterized by resistance (defined as a deficient
urinary cAMP response) to parathyroid hormone and, in most cases, hypocalcemia and
hyperphosphatemia. Many patients with pseudohypoparathyroidism type I snow a peculiar
somatic phenotype termed Albright's hereditary osteodystrophy, but patients without this
feature who show identical parathyroid hormone resistance have been described.
Parathyroid hormone resistance in pseudohypoparathyroidism type I has been attributed to …
urinary cAMP response) to parathyroid hormone and, in most cases, hypocalcemia and
hyperphosphatemia. Many patients with pseudohypoparathyroidism type I snow a peculiar
somatic phenotype termed Albright's hereditary osteodystrophy, but patients without this
feature who show identical parathyroid hormone resistance have been described.
Parathyroid hormone resistance in pseudohypoparathyroidism type I has been attributed to …