A role for brown adipose tissue in diet-induced thermogenesis

NJ Rothwell, MJ Stock - Nature, 1979 - nature.com
NJ Rothwell, MJ Stock
Nature, 1979nature.com
Measurement of energy balance during voluntary over-eating in rats unequivocally
establishes the quantitative importance of diet-induced thermogenesis in energy balance.
Like cold-induced thermogenesis, this form of heat production involves changes in the
activity of the sympathetic nervous system and brown adipose tissue which suggest that this
tissue may determine metabolic efficiency and resistance to obesity.
Abstract
Measurement of energy balance during voluntary over-eating in rats unequivocally establishes the quantitative importance of diet-induced thermogenesis in energy balance. Like cold-induced thermogenesis, this form of heat production involves changes in the activity of the sympathetic nervous system and brown adipose tissue which suggest that this tissue may determine metabolic efficiency and resistance to obesity.
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