Integration of endoplasmic reticulum signaling in health and disease

M Aridor, WE Balch - Nature medicine, 1999 - nature.com
M Aridor, WE Balch
Nature medicine, 1999nature.com
Alteration in the endoplasmic reticulum processing of cargo molecules by pathogens, or
deficiencies in cargo handling by the endoplasmic reticulum machinery in a broad range of
diseases including cystic fibrosis, hemochromatosis and neuropathies such as Alzheimer
disease demonstrates an unanticipated role of the endoplasmic reticulum in the control of
cell fate.
Abstract
Alteration in the endoplasmic reticulum processing of cargo molecules by pathogens, or deficiencies in cargo handling by the endoplasmic reticulum machinery in a broad range of diseases including cystic fibrosis, hemochromatosis and neuropathies such as Alzheimer disease demonstrates an unanticipated role of the endoplasmic reticulum in the control of cell fate.
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