Studies on the expression of genes encoding apolipoproteins B100 and B48 and the low density lipoprotein receptor in nonhuman primates: comparison of dietary fat …
M Sorci-Thomas, MD Wilson, FL Johnson… - Journal of Biological …, 1989 - ASBMB
African green monkeys were fed diets containing low and moderate cholesterol
concentrations with either polyunsaturated or unsaturated fat as 40% of calories. Plasma
total cholesterol, low density lipoprotein (LDL) cholesterol, and apoB concentrations
generally were higher in animals fed (a) the higher dietary cholesterol concentration and (b)
saturated fat. At necropsy, liver and intestine were removed, and measurement of mRNAs for
LDL receptors (liver) and for apolipoprotein B (liver and intestine) was done. Monkey small …
concentrations with either polyunsaturated or unsaturated fat as 40% of calories. Plasma
total cholesterol, low density lipoprotein (LDL) cholesterol, and apoB concentrations
generally were higher in animals fed (a) the higher dietary cholesterol concentration and (b)
saturated fat. At necropsy, liver and intestine were removed, and measurement of mRNAs for
LDL receptors (liver) and for apolipoprotein B (liver and intestine) was done. Monkey small …