t (5; 12)(q31; p12) A clinical entity with features of both myeloid leukemia and chronic myelomonocytic leukemia

JW Wessels, WE Fibbe, D Van Der Keur… - Cancer genetics and …, 1993 - Elsevier
We report two patients with a myeloproliferative disorder (Philadelphia chromosome-
negative chronic myeloid leukemia) and t (5; 12)(q31; p12). Until now, only three cases of a
translocation (5; 12)(q31; p12) have been reported. All investigators had problems
classifying their patient's disease into one of the well-defined entities of either MPD or
myelodysplastic disorders. We postulate that this translocation may represent a subgroup of
patients with features of both chronic myeloid leukemia and chronic myelomonocytic …