Parent-of-origin effect and evidence for differential transmission in periodic catatonia
G Stöber, I Haubitz, E Franzek… - Psychiatric Genetics, 1998 - journals.lww.com
In a family study involving 83 probands with periodic catatonia a subtype of DSM IIIR
schizophrenia, we reported an age-specific morbidity risk of 26.9% in first-degree relatives
with homotypical psychoses and genetic anticipation indicating a possible major gene effect.
Paternal transmission was associated with a trend for a younger age at onset in probands
compared to that observed in the case of maternal transmission (P= 0.099). If this can be
confirmed in a larger sample and then replicated, there would be evidence for the …
schizophrenia, we reported an age-specific morbidity risk of 26.9% in first-degree relatives
with homotypical psychoses and genetic anticipation indicating a possible major gene effect.
Paternal transmission was associated with a trend for a younger age at onset in probands
compared to that observed in the case of maternal transmission (P= 0.099). If this can be
confirmed in a larger sample and then replicated, there would be evidence for the …