The roles of Fas, Fas ligand and Bcl-2 in T cell apoptosis in the central nervous system in experimental autoimmune encephalomyelitis
CA White, PA McCombe, MP Pender - Journal of neuroimmunology, 1998 - Elsevier
The selective apoptotic elimination of autoreactive T cells in the central nervous system
(CNS) contributes to the resolution of inflammation and the spontaneous clinical recovery
from experimental autoimmune encephalomyelitis (EAE). To assess the molecular
mechanisms involved in this process, we used three-colour flow cytometry to examine the
expression of apoptosis-regulating proteins by inflammatory cells isolated from the spinal
cords of Lewis rats immunized with myelin basic protein (MBP) and complete Freund's …
(CNS) contributes to the resolution of inflammation and the spontaneous clinical recovery
from experimental autoimmune encephalomyelitis (EAE). To assess the molecular
mechanisms involved in this process, we used three-colour flow cytometry to examine the
expression of apoptosis-regulating proteins by inflammatory cells isolated from the spinal
cords of Lewis rats immunized with myelin basic protein (MBP) and complete Freund's …