In this review I have emphasized the complicated events that occur during the course of
RDS. RDS is initiated by an inadequate pool size of functional surfactant within a structurally
and functionally immature lung. Obstetric and delivery room management apparently can
significantly influence surfactant function and, therefore, the incidence of RDS, possibly by
affecting the permeability properties of the pulmonary vascular endothelium and alveolar
epithelium. The course and severity of RDS will be further influenced by neonatal care and …