Chemokines and HIV-1 second receptors: the therapeutic connection
JS Cairns, MP D'Souza - Nature Medicine, 1998 - nature.com
JS Cairns, MP D'Souza
Nature Medicine, 1998•nature.comThe discovery that HIV requires a chemokine co-receptor to invade host cells has prompted
many investigations into therapeutic strategies that target these receptors in an attempt to
block HIV entry. In this review, Scott Cairns and Patricia D'Souza discuss these potentially
powerful approaches and how they complement existing antiretroviral drug therapy.
many investigations into therapeutic strategies that target these receptors in an attempt to
block HIV entry. In this review, Scott Cairns and Patricia D'Souza discuss these potentially
powerful approaches and how they complement existing antiretroviral drug therapy.
Abstract
The discovery that HIV requires a chemokine co-receptor to invade host cells has prompted many investigations into therapeutic strategies that target these receptors in an attempt to block HIV entry. In this review, Scott Cairns and Patricia D'Souza discuss these potentially powerful approaches and how they complement existing antiretroviral drug therapy.
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