Translocation of gut bacteria in rats with cirrhosis to mesenteric lymph nodes partially explains the pathogenesis of spontaneous bacterial peritonitis
BA Runyon, S Squier, M Borzio - Journal of hepatology, 1994 - Elsevier
Spontaneous bacterial peritonitis is a common infection of ascitic fluid that develops in
cirrhosis. The offending organisms are predominantly of enteric origin. However, the
mechanism and route by which bacteria exit from the gut and enter the fluid remain
unclear.“Translocation” of bacteria from the gut to extraintestinal sites has been postulated in
the pathogenesis of gram-negative sepsis in intensive care unit patients, burn-wound
sepsis, and sepsis associated with chemotherapy. Translocation is defined by culture …
cirrhosis. The offending organisms are predominantly of enteric origin. However, the
mechanism and route by which bacteria exit from the gut and enter the fluid remain
unclear.“Translocation” of bacteria from the gut to extraintestinal sites has been postulated in
the pathogenesis of gram-negative sepsis in intensive care unit patients, burn-wound
sepsis, and sepsis associated with chemotherapy. Translocation is defined by culture …