Emphysema: the first two centuries and beyond

GL Snider - Am Rev Respir Dis, 1992 - atsjournals.org
GL Snider
Am Rev Respir Dis, 1992atsjournals.org
Two theories of pathogenesis of emphysema dominated the writings of the nineteenth and
early twentieth centuries, the mechanical and the ischemic or atrophic. Excessive inspiratory
force causing damage by stretching of lung tissue was mentioned by some researchers, but
expiratory obstruction wasthe dominant theory. Laennec (17) considered that emphysema
wasa sequel ofa prolonged, minimally productive cough (dry catarrh) that might have begun
in childhood. Emphysema
Two theories of pathogenesis of emphysema dominated the writings of the nineteenth and early twentieth centuries, the mechanical and the ischemic or atrophic. Excessive inspiratory force causing damage by stretching of lung tissue was mentioned by some researchers, but expiratory obstruction wasthe dominant theory. Laennec (17) considered that emphysema wasa sequel ofa prolonged, minimally productive cough (dry catarrh) that might have begun in childhood. Emphysema
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