Elevated soluble CD27 levels in serum of patients with systemic lupus erythematosus
J Font, L Pallares, J Martorell, E Martinez… - Clinical immunology and …, 1996 - Elsevier
The CD27 belongs to the NGF-R, a family of type I transmembrane receptors present in most
T cells. The soluble form of CD27 can be found in body fluids, and elevation of serum levels
is observed in T cell activation. Preliminary studies indicate that measurement of sCD27
levels might be of use in the evaluation of immune responsesin vivo. Systemic lupus
erythematosus (SLE) is a disease of unknown etiology. T cells from SLE patients have
impaired responsiveness to various kinds of stimuli. However, the precise localization of the …
T cells. The soluble form of CD27 can be found in body fluids, and elevation of serum levels
is observed in T cell activation. Preliminary studies indicate that measurement of sCD27
levels might be of use in the evaluation of immune responsesin vivo. Systemic lupus
erythematosus (SLE) is a disease of unknown etiology. T cells from SLE patients have
impaired responsiveness to various kinds of stimuli. However, the precise localization of the …