Differential kinetics of circulating angiotensin IV and II after treatment with angiotensin II type 1 receptor antagonist and their plasma levels in patients with chronic …

Y Shibasaki, Y Mori, Y Tsutumi, H Masaki… - Clinical …, 1999 - europepmc.org
Y Shibasaki, Y Mori, Y Tsutumi, H Masaki, K Sakamoto, S Murasawa, K Maruyama…
Clinical nephrology, 1999europepmc.org
Background Angiotensin II (Ang II) C-terminal hexapeptide (referred to as Ang IV) possesses
the characteristics of a real hormone with specific receptors and biological effects. Clinical
application of Ang II type 1 receptor (AT1-R) antagonists cause an increase in plasma Ang II
level, which may result in enhanced production of Ang IV.
Background
Angiotensin II (Ang II) C-terminal hexapeptide (referred to as Ang IV) possesses the characteristics of a real hormone with specific receptors and biological effects. Clinical application of Ang II type 1 receptor (AT1-R) antagonists cause an increase in plasma Ang II level, which may result in enhanced production of Ang IV.
europepmc.org