Growth factors and cytokines in hair follicle development and cycling: recent insights from animal models and the potentials for clinical therapy
DM Danilenko, BD Ring, GF Pierce - Molecular medicine today, 1996 - Elsevier
Hair growth disorders, particularly those that lead to hair loss (alopecia), are common and
frequently cause significant mental anguish in affected individuals. The mechanisms
underlying the majority of these disorders are unknown. However, insights into the specific
molecular mechanisms of hair follicle development and cycling have recently been made
using animal models, particularly mice that over-or underexpress a specific gene for a
growth factor or cytokine. Other animal models have demonstrated that certain growth …
frequently cause significant mental anguish in affected individuals. The mechanisms
underlying the majority of these disorders are unknown. However, insights into the specific
molecular mechanisms of hair follicle development and cycling have recently been made
using animal models, particularly mice that over-or underexpress a specific gene for a
growth factor or cytokine. Other animal models have demonstrated that certain growth …