Prostaglandin endoperoxide H synthases-1 and-2
WL Smith, DL Dewitt - Advances in immunology, 1996 - Elsevier
Publisher Summary The chapter compares and contrasts the structural and kinetic
properties of prostaglandin endoperoxide H synthase-1 (PGHS-1) and-2. It also discusses
the description of the interactions of the two isozymes with nonsteroidal anti-inflammatory
drugs (NSAIDs). There are three general areas of study important to understanding more
about PGHS isozymes: mechanisms of catalysis, regulation of gene expression, and
subcellular functional independence. The chapter also explain how is arachidonic acid …
properties of prostaglandin endoperoxide H synthase-1 (PGHS-1) and-2. It also discusses
the description of the interactions of the two isozymes with nonsteroidal anti-inflammatory
drugs (NSAIDs). There are three general areas of study important to understanding more
about PGHS isozymes: mechanisms of catalysis, regulation of gene expression, and
subcellular functional independence. The chapter also explain how is arachidonic acid …