Severe deficiency of alpha1-antitrypsin associated with cutaneous vasculitis, rapidly progressive glomerulonephritis, and colitis
M Lewis, J Kallenbach, M Zaltzman, H Levy… - The American journal of …, 1985 - Elsevier
The association of vasculitis with severe deficiency of alpha 1-antitrypsin is rare. This report
describes a 44-year-old man with severe deficiency of alpha 1-antitrypsin associated with
diffuse vasculitis involving skin, kidney (rapidly progressive glomerulonephritis), and colon
(colitis). Colitis has not previously been reported In association with deficiency of alpha 1-
antitrypsin. Other reported cases are reviewed and the possible immunologic mechanisms
underlying the association are discussed.
describes a 44-year-old man with severe deficiency of alpha 1-antitrypsin associated with
diffuse vasculitis involving skin, kidney (rapidly progressive glomerulonephritis), and colon
(colitis). Colitis has not previously been reported In association with deficiency of alpha 1-
antitrypsin. Other reported cases are reviewed and the possible immunologic mechanisms
underlying the association are discussed.