[HTML][HTML] Cloning and Characterization of Cell Adhesion Kinase β, a Novel Protein-tyrosine Kinase of the Focal Adhesion Kinase Subfamily (∗)

H Sasaki, K Nagura, M Ishino, H Tobioka… - Journal of Biological …, 1995 - ASBMB
A second protein-tyrosine kinase (PTK) of the focal adhesion kinase (FAK) subfamily, cell
adhesion kinase β (CAKβ), was identified by cDNA cloning. The rat CAKβ is a 115.7-kDa
PTK that contains N-and C-terminal domains of 418 and 330 amino acid residues besides
the central kinase domain. The rat CAKβ has a homology with mouse FAK over their entire
lengths except for the extreme N-terminal 88 residues and shares 45% overall sequence
identity (60% identical in the catalytic domain), which indicates that CAKβ is a protein …