Regulation of bradykinin-induced chloride secretion in a human epithelial cell line.

DH Miller, AW Baird, S Bennet, M Halushka… - Agents and actions …, 1992 - europepmc.org
DH Miller, AW Baird, S Bennet, M Halushka, M Sasaguri, H Schomer, HS Margolius
Agents and actions. Supplements, 1992europepmc.org
The chloride secretory response to bradykinin in T84 cells is regulated. The efflux rate of
125I from these cells can be used to measure this response, and to demonstrate that the
sensitivity to bradykinin varies with time in culture. The response in NuT84 cells is greater
than that in T84, and can be blocked by the B2 receptor antagonist HOE-140.
The chloride secretory response to bradykinin in T84 cells is regulated. The efflux rate of 125I from these cells can be used to measure this response, and to demonstrate that the sensitivity to bradykinin varies with time in culture. The response in NuT84 cells is greater than that in T84, and can be blocked by the B2 receptor antagonist HOE-140.
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