Angiotensin II receptor subtypes: characterization, signalling mechanisms, and possible physiological implications

SP Bottari, M de Gasparo, UM Steckelings… - Frontiers in …, 1993 - Elsevier
Thanks to the recent discovery of angiotensin II (ANG II) receptor subtypes linked to different
signalling pathways, research in the different areas related to this peptide has regained a
strong interest. In the following review, we first describe the biochemistry and actions of
angiotensin peptides formed both in the circulation and locally at the tissue and organ level.
Evidence for the existence and distribution of ANG II receptor subtypes in mammalian as
well as in nonmammalian species and lower organisms is presented. The changes in …