Chronicity index and mesangial IgG deposition are risk factors for hypertension and renal failure in early IgA nephropathy

C Nieuwhof, M Kruytzer, P Frederiks… - American journal of …, 1998 - ajkd.org
To determine the natural history in early immunoglobulin A (IgA) nephropathy, we evaluated
the long-term follow-up of 27 normotensive nonazotemic adult idiopathic IgA nephropathy
patients with chronic hematuria who derived from a prospective regional epidemiological
study of glomerulonephritis conducted between 1978 and 1984. As controls, 17 thin
glomerular basement membrane (GBM) patients, 24 patients with normal renal tissue, and
nine patients with miscellaneous nephropathies were followed up. Median follow-up was 11 …