Simultaneous engraftment of maternal T cells and T cells from unrelated transfusion donor in
an infant with severe combined immunodeficiency disease (SCID) was identified by HLA
typing blood lymphocytes of the patient, her triplet siblings, parents, and the platelet donor
from whom the patient received nonirradiated platelet transfusion. T cell grafts from both the
mother and platelet donor were stable for several months, but the graft-versus-host reactions
(GvHR) remained mild and immune function was deficient. We hypothesize that …