[40] Preparation and characterization of chloramines

EL Thomas, MB Grisham, MM Jefferson - Methods in enzymology, 1986 - Elsevier
Publisher Summary This chapter discusses the preparation and characterization of
chloramines. Chloramines represent an important class of leukocyte oxidants and contribute
to oxidative microbicidal, cytotoxic and cytolytic activities, the chemical modification of
regulatory substances, and the uptake and metabolism of nitrogen compounds. These are
products of the reaction of hypochlorous acid (HOCl) or other chlorinating agents with
primary and secondary amines. The production of HOCl by leukocytes is the result of …