Airway hyperresponsiveness, increased intracellular spaces of bronchial epithelium, and increased infiltration of eosinophils and lymphocytes in bronchial mucosa in …

Y Ohashi, S Motojima, T Fukuda, S Makino - Am Rev Respir Dis, 1992 - atsjournals.org
Y Ohashi, S Motojima, T Fukuda, S Makino
Am Rev Respir Dis, 1992atsjournals.org
Inflammation of the airway wall and airway hyperresponslveness are consistent features of
chronic asthma. We investigated how damage of the bronchial epithelium Is related to
airway hyperresponslveness and how bronchial Infiltration of eoslnophils and lymphocytes
Is related to bronchial epithelial damage. Weexamined the biopsy specimens of bronchial
mucosa taken from 19 patients with chronic asthma by electron microscopy. Wealso
measured the incidence of open-
Summary
Inflammation of the airway wall and airway hyperresponslveness are consistent features of chronic asthma. We investigated how damage of the bronchial epithelium Is related to airway hyperresponslveness and how bronchial Infiltration of eoslnophils and lymphocytes Is related to bronchial epithelial damage. Weexamined the biopsy specimens of bronchial mucosa taken from
19 patients with chronic asthma by electron microscopy. Wealso measured the incidence of open-
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