Arterial walls generate from prostaglandin endoperoxides a substance (prostaglandin X) which relaxes strips of mesenteric and coeliac arteries and inhibits platelet …
S Bunting, S Moncada, JR Vane, R Gryglewski - Prostaglandins, 1976 - Elsevier
Fresh arterial tissue generates an unstable substance (prostaglandin X) which relaxes
vascular smooth muscle and potently inhibits platelet aggregation. The release of
prostaglandin (PG) X can be stimulated by incubation with arachidonic acid or prostaglandin
endoperoxides PGG 2 or PGH 2. The basal release of PGX or the release stimulated with
arachidonic acid can be inhibited by previous treatment with indomethacin or by washing
the tissue with a solution containing indomethacin. The formation of PGX from prostaglandin …
vascular smooth muscle and potently inhibits platelet aggregation. The release of
prostaglandin (PG) X can be stimulated by incubation with arachidonic acid or prostaglandin
endoperoxides PGG 2 or PGH 2. The basal release of PGX or the release stimulated with
arachidonic acid can be inhibited by previous treatment with indomethacin or by washing
the tissue with a solution containing indomethacin. The formation of PGX from prostaglandin …