The effects of leukocyte-endothelium adhesion on microhemodynamics were studied in cat
mesentery under control conditions and following tissue suffusion with the chemotactic
agent N-formyl-methionyl-leucyl-phenylalanine (FMLP). The results indicate that under
normophysiological conditions there is little or no leukocyte-endothelium adhesion in
arterioles and venules. Tissue suffusion with FMLP significantly increases the number of
adhering leukocytes in venules, but not in arterioles. Analysis of the number of adhering …