Characterization and gene sequence of the precursor of elafin, an elastase-specific inhibitor in bronchial secretions

JM Sallenave, A Silva - American journal of respiratory cell and …, 1993 - atsjournals.org
JM Sallenave, A Silva
American journal of respiratory cell and molecular biology, 1993atsjournals.org
Characterization and Gene Sequence of the Precursor of Elafin, an Elastase-specific Inhibitor
in Bronchial Secretions Page 1 Characterization and Gene Sequence of the Precursor of
Elafin, an Elastase-specific Inhibitor in Bronchial Secretions Jean-Michel Sallenave and
Anabel Silva Department of Biochemistry, Edinburgh University Medical School, Edinburgh,
United Kingdom Human bronchial mucous secretions have been shown to contain inhibitors
of serine proteinases secreted by neutrophils. The role of these inhibitors is probably to control …
Materials and Methods
Biologic Material A pool of sputa (250 ml) from patients with chronic bronchitis was collected and stored at-20 C until use.
ATS Journals