Constitutive and induced expression of APO-1, a new member of the nerve growth factor/tumor necrosis factor receptor superfamily, in normal and neoplastic cells.
F Leithäuser, J Dhein, G Mechtersheimer… - … ; a journal of technical …, 1993 - europepmc.org
F Leithäuser, J Dhein, G Mechtersheimer, K Koretz, S Brüderlein, C Henne, A Schmidt…
Laboratory investigation; a journal of technical methods and pathology, 1993•europepmc.orgConstitutive and induced expression of APO-1, a new member of the nerve growth factor/tumor
necrosis factor receptor superfamily, in normal and neoplastic cells. - Abstract - Europe PMC
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necrosis factor receptor superfamily, in normal and neoplastic cells. - Abstract - Europe PMC
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Background
APO-1 is a 48 kilodalton transmembrane, cysteine-rich glycoprotein identical with the Fas antigen which belongs to the nerve growth factor/tumor necrosis factor receptor superfamily. Cross-linking of APO-1 induces apoptotic cell death in sensitive cells.
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