Cloning of the cDNA for a rat intestinal Na+/dicarboxylate cotransporter reveals partial sequence homology with a rat intestinal mucin
IA Khatri, SVB Kovacs, JF Forstner - Biochimica et Biophysica Acta (BBA) …, 1996 - Elsevier
In this report we present the full-length cDNA and deduced 587 amino acid sequence of a
putative rat intestinal Na+/dicarboxylate cotransporter. It shows sequence and structural
similarity to a rabbit renal Na+/dicarboxylate cotransporter. An unexpected fining was the
presence of a C-terminal transmembrane region that is homologous with an 87 amino acid
hydrophobic region of a rat intestinal mucin, M2. Mucin-related sequences in transporter
proteins have not been described before.
putative rat intestinal Na+/dicarboxylate cotransporter. It shows sequence and structural
similarity to a rabbit renal Na+/dicarboxylate cotransporter. An unexpected fining was the
presence of a C-terminal transmembrane region that is homologous with an 87 amino acid
hydrophobic region of a rat intestinal mucin, M2. Mucin-related sequences in transporter
proteins have not been described before.